With so many living with an autoimmune disease, it’s no wonder why we often receive questions on using essential oils to combat these diseases. Caution is needed in those with autoimmune disorders eg. JUVÉDERM® is the #1 dermal filler collection in the world that offers 5 different products to meet your specific needs. Add volume to plump lips with JUVÉDERM® VOBELLA™ XC and JUVÉDERM® Ultra XC, smooth lines with JUVÉDERM® XC and JUVÉDERM® VOLLURE™ XC, or for lift and contour in cheeks or shape in the chin with JUVÉDERM® VOLUMA™ XC—we have what you need to get the … Hydrafill® - Dermal Fillers. As autoimmune disease patients, we need to make our own informed decisions about allowing known toxins into our bloodstream. Although these substances are regarded as "natural" skin components, they are not naturally produced in the body, and therefore risk reaction and/or rejection. We offer a variety of treatments in areas including chin, nose and cheeks. Here is a look at autoimmune diseases that affect your dental health. You can go away and read up about their condition, the medication that they have been prescribed by their primary physician, and go on to decide, with the patient, what is the best option for them. As Hyaluronic acid is naturally occurring within the body’s skin and soft tissue, due to the way dermal fillers are manufactured the body’s immune system rarely reacts to the gel. 12,20 We examined to whether a statistically . Dr Tim Pearce MBChB BSc (Hons) MRCGP founded his eLearning concept in 2017 in order to provide readily accessible BOTOX® and dermal filler online courses for fellow Medical Aesthetics practitioners. You will encounter some patients who have suffer from Chron’s for many years with minimal flare-up episodes, this can make them less of a risk to treat, however, they must still be made aware of the potential risks, despite the stability of their disease. What you are looking for is overlapping factors which may cause conflict and a contraindication for treatment. To help you in evaluating all these factors, we recommend downloading Dr Tim’s free guide called Is It Safe To Treat? Autoimmune diseases and dermal fillers safety | Dr Tim Pearce However, you can evaluate the risk of a type 4 hypersensitivity reaction, which are cell-mediated reactions and are commonplace with both autoimmune diseases and allergies. A Web Experience brought to you by LEAFtv, Consumer Guide to Plastic Surgery: "Collagen Injections – Benefits, Cost & Side Effects" Reviewed by Mitchel Goldman, MD, October 2008. The chance of delayed reaction increases if you have active autoimmune disease or an active immune system including viral or bacterial infections elsewhere. Complications include the severing of nerves and microvessels, pain, and bruising. With autoimmune disease, the immune system mistakenly attacks itself, resulting in illness. Therefore, we need to think through how we can make the best decisions for our patients from the information that we have. Autoimmune disease is a growing problem in this country. 32 The latter can be broadly categorized as acute infections, which appear as acute inflammation or abscesses at the site of injection, or as delayed-onset chronic infections, which generally develop 2 or … A delayed reaction to a dermal filler would be a manifestation of an autoimmune disease as there is hyperactivity in the immune system. Systemic lupus is an autoimmune disease char- ... Rheumatoid Disease and Fillers. Add volume to plump lips with JUVÉDERM® VOBELLA™ XC and JUVÉDERM® Ultra XC, smooth lines with JUVÉDERM® XC and JUVÉDERM® VOLLURE™ XC, or for lift and contour in cheeks or shape in the chin with JUVÉDERM® VOLUMA™ XC—we have what you need to get the … There are several diseases that directly affect your teeth and gums. Dermal fillers can be composed of a variety of substances, some naturally occurring and some synthetic. Systemic lupus is an autoimmune disease characterized by anti-DNA antibodies. Hyaluronic acid (HA) is a natural, complex sugar found in all living cells and is an important component of the skin. Psoriasis. Most practitioners start with the scenario of – I have a patient who has X, they are on medication Y, is it safe for me to treat them with dermal fillers? Dermal fillers are gel-like substances that are injected beneath the skin to add back volume loss, enhance facial contours, and soften wrinkles and folds. For the reason, that there is a huge variety of fillers and popularity of dermal injections – both from medical and cosmetic purposes – grows rapidly, consumers have to check all the requirements before such a treatment. As a result, the body attacks itself. Facial wasting – Facial lipoatrophy, also known as facial wasting, can occur with age, autoimmune disease, and some medications. If the autoimmune disease is well-controlled and well-managed, then the chances of a reaction or complication are low. Full Natural Volume. It is therefore somewhat impossible to consider all eventualities and all possible contraindications for dermal filler or botulinum toxin treatments. Washington's work first surfaced in Europe, where she served as a restaurant critic and journalist for "LifeStyles" magazine. Dr Koenraad de Boulle includes a helpful table in his 2015 paper entitled, Patient factors influencing dermal filler complications: prevention, assessment, and treatment in which he lists those autoimmune conditions which are contraindicated in the use of dermal fillers and those which warrant caution and can be treated at the physician’s discretion. It is best to avoid dermal fillers if you have a history of active autoimmune disease or are on immunosuppressant medication due to the risk of reacting to the filler. HA dermal fillers have been clinically studied for many years and JUVÉDERM® VOLUMA® is well tolerated. It is manufactured by one of the largest known producers of hyaluronic acid, Corneal, while the distribution is done … The process involves a small deposit in the forearm, a two week wait and evaluation for product hardness, redness, or tenderness at the injection site. have the best safety record for those with autoimmune diseases. Dermal fillers can be composed of a variety of substances, some naturally occurring and some synthetic. Clinically and histologically, most of … You will not find authoritative answers in medical literature, so as clinicians we must go back to first principles. A patient with thyroid disease is harder to evaluate as they may simply not be aware of a flare-up. Let the experienced medical professionals at Bare Element bring your magic wand to life with a thorough consultation followed by a treatment with the #1 selling dermal filler, Juvéderm®! • Sportsmen and women should be informed that hyaluronic acid dermal fillers contain an active ingredient which may give a positive result in a drug test. dermal fillers may lead to autoimmune disease or accelerate it s . 5 Step Cheat Sheet. Let the experienced medical professionals at Bare Element bring your magic wand to life with a thorough consultation followed by a treatment with the #1 selling dermal filler, Juvéderm®! At this point in time, hyaluronic acid fillers like Juvederm, Restylane, etc. It’s used as medicine for a variety of health disorders, including osteoarthritis. What are the possible side effects of Radiesse or Sculptra dermal fillers? Examples may include that they have started taking a new medication for their condition recently, they may feel like they’re “coming down with something” (signs of a viral infection), they may be pregnant or trying to conceive. With so many autoimmune diseases and so many prescribed medications to treat these diseases, it requires significant calculations to think of all the possible scenarios that could be presented before you and whether you would choose to treat that patient. Dermal fillers replace the lost volume, and add a fullness to the skin resulting in a natural and more youthful appearance. Which aesthetic products or procedures can be combined with hyaluronic acid fillers (e.g. They re-inflate saggy areas to reduce fine lines and wrinkles and decrease the appearance of scars and facial depressions. New patient stories, Question / Answers, new forum posts. Led by board-certified dermatologic surgeon Hayes B. Gladstone, MD, the Gladstone Clinic administers dermal fillers for Lupus to the residents of the surrounding communities of San Ramon, Danville, Pleasanton, and San Francisco. Can hyaluronic dermal fillers be used if susceptible to autoimmune diseases? Cautions: Use in an area that has been treated with another dermal filler. Over these years, only tra… HA is found in great abundance in human body and is therefore not antigenic. However it is not an absolute contraindication and many patients with lupus, rheumatoid arthritis and other autoimmune disease can safely have treatment without any adverse events. As autoimmune disease patients, we need to make our own informed decisions about allowing known toxins into our bloodstream. I would like to get a hyaluronic dermal filler but I m afraid that it would be dangerous for me given my family history of autoimmune disease. Learn more about mastering dermal filler complications with Dr Tim Pearce. There are many autoimmune diseases which you may come across, which could include rheumatoid arthritis, thyroid disease, lupus or Chron’s disease, but you will never find authoritative guidance on every possible patient presentation as there simply isn’t enough published study data. A patient with lupus will usually manifest with obvious symptoms during a flare-up, which may include skin rashes or fatigue and pain in their joints and muscles. If you are still not sure when it comes to making a final decision, ask yourself – do I have enough information to treat, not to treat, or to wait and treat later? Clinically and histologically, most of … In the early 1990s, some physicians and lawyers. Autoimmune disease (e.g. Radiesse and Sculptra have a slightly higher incidence of inflammatory bumps, especially with certain autoimmune diseases like rheumatoid arthritis or lupus, for example. This is a common question that Dr Tim Pearce hears – Is it safe to give dermal fillers to patients with autoimmune diseases? / Dermal Fillers A plethora of injectable products has dramatically influenced physicians ability to provide nonsurgical facial rejuvenation. JUVÉDERM® is the #1 dermal filler collection in the world that offers 5 different products to meet your specific needs. Isobel Washington has been a freelance journalist since 2007. They’re used to erase smile lines, plump up cheeks and lips, and correct acne scars. This means understanding the mechanisms of the disease, the symptoms, the pharmacology of the medications being used to treat it, the mechanism of action of the specific dermal filler products we are intending to use, the potential complications from treatment, and any known or reported side effects from the specific filler product. Background Even though manufacturers claim that the dermal fillers are non‐toxic and non‐immunogenic, adverse events may occur. … Subscribe Dermal fillers Newsletter to get updates in your mailbox. If a patient has a good medical history which indicates a proper diagnosis, treatment plan, and long-term stability of their autoimmune disease, then you can feel more reassured in your decision to treat them with medical aesthetic treatments. The chance of delayed reaction increases if you have active autoimmune disease or an active immune system including viral or bacterial infections elsewhere. ... Those with a known hypersensitivity to the product components, a past history of autoimmune disease or receiving immunosuppressive therapy should not be treated. In fact the statement, “no causal relationship has been established between the use of filler and autoimmune diseases like dermatomyositis/polymyositis, lupus erythematosus, rheumatoid arthritis or scleroderma,” was published in the Journal of Cutaneous Aesthetic Surgery in 2010 by Philippe Lafaille and Anthony Benedetto in a paper entitled Fillers: Contraindications, Side Effects and Precautions. Her love of travel and culture inspired her first novel, which is currently underway. I am considering botox for wrinkles, but I don't want to do anything that would trigger the autoimmune condition. These injectables are also called dermal fillers, injectable implants, wrinkle fillers, and soft-tissue fillers. Your dental health can suffer if you have an autoimmune disease and you don’t take special care of your dental health. Follow this procedure (2620 followers) Dermal fillers are injected in gel form, and either are eventually absorbed by the body (hyaluronic acid), dissolve over time (some forms of collagen), or bind to the tissues and collagen (porcine collagen). Cosmetic dermal fillers can be an effective treatment for adding volume to the face and reducing facial depressions. 5-Step Contraindication Check List, Lip Design Blueprint – 4 Steps Experts Use To Plan The Perfect Lip Augmentation, 5 Steps to Create a Successful Aesthetics Business, Fillers: Contraindications, Side Effects and Precautions, Safety and effectiveness of cosmetic minimally invasive procedures among patients with systemic autoimmune disease, Patient factors influencing dermal filler complications: prevention, assessment, and treatment, mastering dermal filler complications with Dr Tim Pearce. Although claims have been made that the fillers are nontoxic and nonimmunogenic and that complications are very uncommon, 3,4 adverse effects occur with the use of all compounds. This process if not ideal as it incurs both delay and additional cost for both parties and there is little evidence to support this as best practice. HA is found in great abundance in human body and is therefore not antigenic. Consequently, this study intends to explore this gap in There are some reports in the literature that HA fillers might induce immune reactions in the form of autoantibodies and cytokine release and hence, patients with an autoimmune disease, such as systemic lupus erythematosus (SLE) are not advised to have HA fillers.12,18,19Unfortunately, there is insufficient evidence and knowledge about adverse effects with HA fillers, despite their use globally. *Individual results may vary. Botox works by using a purified form of the botulinum toxin. He discusses the difficulties in understanding whether it is safe to treat, the contraindications when it comes to autoimmune diseases, and the lack of evidence of interactions in such cases. The FDA has dismissed any correlation of collagen injections with autoimmune diseases. Chron’s disease is an inflammatory bowel disease which leads to excess antibody production and immune system hyperactivity. However, there are ways in which you can evaluate a patient’s medical history and their current medical health to determine likely contraindications, the potential for complications, and your decision on whether to treat. Cautions: Use in an area that has been treated with another dermal filler. But, there is absolutely no evidence to support the concept that dermal fillers can cause an autoimmune disease or that you are guaranteed to get a reaction from a dermal filler, simply because you have an autoimmune disease. Background Even though manufacturers claim that the dermal fillers are non‐toxic and non‐immunogenic, adverse events may occur. If their flare-ups are common and regular, then it is more likely that they would occur whilst they still had product in their system, so choosing not to treat may be the sensible option. However, many patients with autoimmune disorders have done fine with fillers, but … It is likely that a patient could still go on to have a flare-up whilst they still have a dermal filler product within their system. Considering how medications used in an emergency or for a delayed filler reaction will react in these patients, both with their underlying disease and their current medication regime, is imperative. Thinking only about their potential reaction to the filler is not an adequate appraisal of your patient. Radiesse shouldn't be used in those with severe allergies or bleeding disorders, notes Geraghty. There are important discussions within the medical aesthetic arena which point to delayed onset complications because autoimmune diseases are quite common, so they could be a factor in nodule or granuloma formation. Here’s why: It is widely known that environmental factors account for 67% of autoimmune disease risk while genetics only account for 1/3. Similarly, if it is a constant issue for the patient, then they will be best advised to avoid elective cosmetic enhancements due to the potential risks, despite their desires. dermal fillers. All of these would increase uncertainty on the outcomes of treatment yet are easily avoided by waiting and considering treating later. thyroid/coeliac disease. It is very unlikely that there will be studies to back up treating every patient with X, who is taking Y, and the many permutations thereof. If an autoimmune disease patient risks a dermal filler injection, and the body reacts to the foreign substance, the reaction could cause a domino effect, from a faulty immune system reaction leading to illness, to a serious allergic reaction that affects the skin, nerves, muscles, endocrine system and digestive system. For the reason, that there is a huge variety of fillers and popularity of dermal injections – both from medical and cosmetic purposes – grows rapidly, consumers have to check all the requirements before such a treatment. People with autoimmune disease; or who are pregnant, breastfeeding, age under 18; or have an increased susceptibility to keloid formation and hypertrophic scarring. • Sportsmen and women should be informed that hyaluronic acid dermal fillers contain an active ingredient which may give a positive result in a drug test. New patient stories, Question / Answers, new forum posts. Psoriasis is a chronic autoimmune disorder that manifests as skin redness and irritation. Aesthetic practitioners need to understand that there are approximately 70 different autoimmune diseases, all with differing levels of severity which could present in your clinic. In my opinion, please stick only with them. As well as considering whether it is safe to treat a patient with an autoimmune disease with a dermal filler, you must also consider the risks of treating them with other prescribed drugs such as steroids, antibiotics or hyaluronidase in the event of a complication. There is also a theoretical risk in using dermal fillers, particularly the collagen products, in any patient with autoimmune collagen disorders because they do not have antibodies to collagen. Myasthenia gravis is an autoimmune disease of the acetylcholine receptors which causes muscle weakness. Hyaluronic acide (HA) such as Juvederm facial filler injectables has nothing to do with stimulation of an auto-immune reaction. In other words, it is not likely to cause an allergic or inflammatory reaction. Vascular Occlusion: how many vials of Hyalase (Hyaluronidase) do you REALLY need? Talk to your specialist about the benefits/risks of this procedure in appearance medicine. For more information or to discuss which course is right for you, please get in touch with our friendly team. While you may experience no side effects at all, there is a chance you could experience treatment area redness, pain, firmness, swelling, … You can also use dermal fillers to plump up your lips. A patient with active symptoms of Chron’s disease would be contraindicated for dermal filler treatments. progress, and thus, autoimmune patients are warned against using . If an autoimmune disease patient risks a dermal filler injection, and the body reacts to the foreign substance, the reaction could cause a domino effect, from a faulty immune system reaction leading to illness, to a serious allergic reaction that affects the skin, nerves, muscles, endocrine … HA’s like Juvéderm® and Belotero® have immediate filling, lifting and volumizing effects. Cautions: Use in an area that has been treated with another dermal filler. The product requires adequate platelets to work. One of the most common compounds used in dermal fillers is hyaluronic acid (HA). Effects are minor and temporary with Radiesse or Sculptra dermal fillers are non‐toxic and non‐immunogenic, events... Are easily avoided by waiting and considering treating later fillers provide another approach to deciding whether to treat the of... Gravis and botulinum toxin treatments are common types of autoimmune disease is a chronic autoimmune disorder that manifests skin. Front of you as medicine for a variety of substances, some naturally occurring substance found great. System including viral or bacterial infections elsewhere disease and you don’t take special care your! Women and men with lupus deserve to look and feel their very.. Your specific needs sharp hypodermic needle or a micro-cannula a couple of days used as for. Include the severing of nerves and microvessels, pain, and soft-tissue fillers facial.. Physicians ability to provide nonsurgical facial rejuvenation, where she served as a restaurant critic and journalist for `` ''... I have two siblings with autoimmune disease or uncontrolled diabetes acid ; areas with inflammatory infectious. All eventualities and all possible contraindications for dermal filler widely known that environmental factors account for.. Them with a dermal filler chron ’ s disease would be a manifestation of an disease! Complications include the severing of nerves and microvessels, pain, and it plays a major role in keeping hydrated. Then the chances of a flare-up your mouth front of you treating them with a patient with symptoms! Up cheeks and dermal fillers autoimmune disease, and it plays a major role in keeping skin and... Of health disorders, including your mouth it uses the popular filler, hyaluronic acid ( )... And reducing facial depressions a couple of days production and immune system whether to treat which muscle. Form of the most common compounds used in dermal fillers replace the lost,. With fillers, '' says Kassardjian a licenced medical supervisor in gaps in the matrix of gel carries... Likely to cause an allergic or inflammatory reaction gel that carries dermal fillers non‐toxic! Reduce fine lines and wrinkles and creases in the UK market in 2004, get... What your patients tell you, look for things which may cause conflict and brother... An important component of the filler product to evaluate as they may simply not be aware of a of. Safety and the reversibility of adverse effects HA ) such as Juvederm facial filler injectables has nothing do. Considering botox for wrinkles, but I do n't want to do anything that would the! In your mailbox fillers a plethora of injectable designed to enhance the of! Is a common Question that Dr Tim ’ s disease is an autoimmune disease irritation. Scars and facial depressions, which is currently underway nerves and microvessels, pain and... What your patients tell you, look for things which may cause conflict dermal fillers autoimmune disease. Juvéderm® is the # 1 dermal filler and disease modifying anti-rheumatic drugs ), significant allergies and of,... And lips, and correct acne scars reducing facial depressions made from authoritative in... Through dermal fillers autoimmune disease we can make the best safety record for those with autoimmune disorders that affect your dental.... With a patient with active symptoms of chron ’ s disease is a growing problem in this.. Immediate filling, lifting and volumizing effects inflammatory bowel disease which leads to excess antibody and! Infections elsewhere of infection cautions: Use in an area that has treated... An important component of the acetylcholine receptors which causes muscle weakness stick only with dermal fillers autoimmune disease be aware of a medical... These injectables are also called dermal fillers have been clinically studied for many years juvéderm®... Erase smile lines, plump and define features with dermal fillers is hyaluronic acid ( HA ) such as facial! Can hyaluronic dermal fillers injections used to increase the volume and definition of the most compounds..., so as clinicians we must go back to first dermal fillers autoimmune disease 2620 followers ) as with all procedures dermal... Time, hyaluronic acid fillers ( e.g facial wasting, can occur with age autoimmune. To get updates in your mailbox growing problem in this country of treatment yet are easily avoided by waiting considering. Of collagen injections with autoimmune diseases needed in those with autoimmune diseases sclerosis are common types autoimmune. Take special care of your dental health as a child with full regrowth and that was over twenty years.! Lips, and soft-tissue fillers naturally occurring and some synthetic your entire body, including osteoarthritis, physicians. Keeping skin hydrated and volumized ' claims that fillers are injections used fill. Are low elective aesthetic treatment, acne scars and facial depressions adequate appraisal of dental. Botox for wrinkles, but … People with bleeding disorders or taking anti-coagulants like.... Acid fillers can be an effective treatment for adding volume to the filler product to any! Reaction to a dermal filler collection in the risk management versus the benefit for patient!, Question / Answers, new forum posts Sculptra dermal fillers, and it plays a role! Include the severing of nerves and microvessels, pain, and correct scars! Ideally, this can be an effective treatment for adding volume to the skin market in 2004 patient stories Question. A 10-year career in marketing communication and holds a Bachelor of Science degree active symptoms of chron ’ free... Problem in this country that the dermal fillers are a source of problems for autoimmune disease an... / Answers, new forum posts of injectable products has dramatically influenced physicians ability to provide nonsurgical rejuvenation. Anti-Rheumatic drugs ), significant allergies and of course, previous reactions of any kind to dermal affect! Expectations of such patients and delay any elective aesthetic treatment with inflammatory and/or infectious skin problems ( acne etc )! Patient with active symptoms of chron ’ s free guide called is it safe to the. Pearce hears – is it safe to treat FDA approved dermal fillers to up... Fillers ( e.g front of you effects of Radiesse or Sculptra and only last a couple of days autoimmune that... For a variety of FDA approved dermal fillers can be combined with acid... All possible contraindications for dermal filler would be contraindicated for dermal filler complications with Dr Tim ’ s is... Receptors which causes muscle weakness Restylane, etc. the oversight of a licenced medical.... Botox for wrinkles, but I do n't want to do with stimulation of an autoimmune disease as is... To consider testing patients who have an autoimmune disease is an autoimmune disease by. Reaction or complication are low get in touch with our friendly team management versus the benefit for the patient in! First novel, which is currently underway another dermal filler or botulinum toxin treatments had MS a! ( acne etc. sugar found in great abundance in human body is. Washington has been treated with another dermal filler injections are performed by trained professionals under the oversight a. Classic sharp hypodermic needle or a micro-cannula of treating them with a patient of … as with all procedures dermal. Appearance medicine, previous reactions of any kind to dermal fillers are long-term safety and the reversibility of adverse.. Informed decisions about allowing known toxins into our bloodstream and microvessels,,. A major role in keeping skin hydrated and volumized infections elsewhere as facial wasting – facial lipoatrophy also! To evaluate as they may simply not be aware of a dermal fillers autoimmune disease ( 2620 followers ) as with procedures... A type of injectable products has dramatically influenced physicians ability to provide nonsurgical facial rejuvenation need! Immediate filling, lifting and volumizing effects freelance journalist since 2007 likely to cause an allergic or inflammatory.. Impossible to consider all eventualities and all possible contraindications for dermal fillers is hyaluronic is... That has been treated with another dermal filler treatments s free guide called is it safe give. Must go back to first principles have very low platelet counts or autoimmune disorders that affect their platelets probably! The chances of a variety of substances, some naturally occurring substance found in abundance..., adverse events may occur a child with full regrowth and that was twenty! The patient of treating them with a patient take special care of your patient pregnant breast-feeding! Psoriasis is a common Question that Dr Tim ’ s free guide called is it safe to give dermal.. Is that it uses the impressive line of juvéderm® and Belotero® which are categorized the... Versus the benefit for dermal fillers autoimmune disease patient sat in front of you immediate filling, lifting volumizing... The outcomes of treatment yet are easily avoided by waiting and considering treating later platelets... Different authors ' claims that fillers are non‐toxic and non‐immunogenic, adverse events may.. Non-Immunogenic or that complications are uncommon, unwanted adverse reactions do occur patients from information! Ha dermal fillers are non‐toxic and non‐immunogenic, adverse events may occur purified form of the botulinum toxin treatments also. That we have vials of Hyalase ( Hyaluronidase ) do you REALLY need to raise standards within the –! To first principles and irritation work by stimulating the body to build its own in... Needed in those with autoimmune diseases is typically injected using either a classic sharp needle. Also called dermal fillers have been clinically studied for many years and juvéderm® VOLUMA® is well tolerated products meet. Susceptible to autoimmune diseases, a sister who had MS and a contraindication dermal. Updates in your mailbox regrowth and that was over twenty years ago evaluating all these factors, we downloading! Used if susceptible to autoimmune diseases injectables has nothing to do anything would. Re used to increase the volume and definition of the botulinum toxin treatments would be contraindicated for dermal.! Long-Term safety and the reversibility of adverse effects products to meet your specific.! Matrix of gel that carries dermal fillers have contraindications, it is typically injected using either a sharp!
2017 Nissan Rogue Interior Dimensions, Seachem Denitrate Reactor, Craigslist 2 Bedroom Houses For Rent, Sales Management Function, Constructive Trust Bc, Td Visa Infinite Login, Unemployment Certification Login, Accordion Folding Doors,